Towards Simultaneous Electrical and Optical Investigation of Blms Using a Novel Microfluidic Device
نویسندگان
چکیده
We firstly describe the influence of the phospholipid (PL) composition of bilayer lipid membrane on their electrical properties: (i) the more unsaturations in the tail, the earlier the BLM breakdown and (ii) the bulkier the head group, the less stable the membrane. Secondly, we design and fabricate novel devices that couple such electrical characterization to optical investigation and that enable the preparation of asymmetrical membranes: a “macro” device including a drilled PMMA plate as well as microfluidic device consisting of a glass-teflon foil-glass sandwich.
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